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innovation


April 2026 | De-Risking What Matters

Apr 30, 2026

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4 min read

April 2026 | De-Risking What Matters

Drug development improves when benefit and harm are quantified earlier, new data are generated for a defined purpose, and every tool is tied to a real decision.

Szczepan Baran
Brian Berridge
Nick Kelley
Szczepan Baran, Brian Berridge, Nick Kelley
Your Pipeline Dies in the Overlap

Apr 8, 2026

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5 min read

Your Pipeline Dies in the Overlap

A practical way to fund only the data that changes decisions, using three curves and one rule: reduce overlap or stop spending

Szczepan Baran
Szczepan Baran
It’s time for subtractive innovation in drug development

Jan 29, 2026

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10 min read

It’s time for subtractive innovation in drug development

A dog wagging the tail strategy

Brian Berridge
Brian Berridge

Innovation to Impact;
Ruminations & Ramblings

From idea to impact: candid reflections and sharp provocations on the real journey of innovation in drug development.