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The Horse is Out of the Barn

Aug 14, 2026

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5 min read

The Horse is Out of the Barn

Clinical barriers to preclinical success

Brian Berridge
Brian Berridge
The Context of Use Conundrum

Aug 2, 2026

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7 min read

The Context of Use Conundrum

A scoping challenge

Brian Berridge
Brian Berridge
Blissful Ignorance

Jul 26, 2026

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6 min read

Blissful Ignorance

"Filling the void"

Brian Berridge
Brian Berridge
April 2026 | De-Risking What Matters

Apr 30, 2026

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4 min read

April 2026 | De-Risking What Matters

Drug development improves when benefit and harm are quantified earlier, new data are generated for a defined purpose, and every tool is tied to a real decision.

Szczepan Baran
Brian Berridge
Nick Kelley
Szczepan Baran, Brian Berridge, Nick Kelley
Your Pipeline Dies in the Overlap

Apr 8, 2026

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5 min read

Your Pipeline Dies in the Overlap

A practical way to fund only the data that changes decisions, using three curves and one rule: reduce overlap or stop spending

Szczepan Baran
Szczepan Baran
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Innovation to Impact;
Ruminations & Ramblings

From idea to impact: candid reflections and sharp provocations on the real journey of innovation in drug development.